Constant Light Dysregulates Cochlear Circadian Clock and Exacerbates Noise-Induced Hearing Loss
نویسندگان
چکیده
منابع مشابه
Preconditioning by the inhalation of pure oxygen protects rat’s cochlear function against noise-induced hearing loss
Background: Occupational noise-induced hearing loss (ONIHL) is a hearing disorder that affects workers all over the world. Preconditioning with several mild or less potent stressors will effectively prevent the development of noise-induced hearing loss. This study investigated the possible preventive effects of normobaric hyperoxia preconditioning on preventing the noise-induced hearing impairm...
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Recent studies on animal models have shown that noise exposure that does not lead to permanent threshold shift (PTS) can cause considerable damage around the synapses between inner hair cells (IHCs) and type-I afferent auditory nerve fibers (ANFs). Disruption of these synapses not only disables the innervated ANFs but also results in the slow degeneration of spiral ganglion neurons if the synap...
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This paper presents noise problems associated with the use of air-turbine drills in dental practice. Two hundred and fifty dentists (male and female) were randomly selected from the faculty of dentistry as well as the dentists who worked private in Tehran. The results indicated that the mean value of sound pressure level produced by the high-speed drills was 69.1 db. Most of the energy from...
متن کاملAcrylonitrile produces transient cochlear function loss and potentiates permanent noise-induced hearing loss.
There is growing evidence that agents that produce oxidative stress in the cochlea have significant ototoxic potential by themselves and can potentiate noise-induced hearing loss as well. Acrylonitrile (ACN) metabolism entails conjugation with glutathione, resulting in rapid and pronounced depletion of this important antioxidant in many organs including brain, liver, and kidney. ACN metabolism ...
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conclusions despite rising figures of reported occupational hearing loss, working nbii statistics show that the nihl problem in the danish work environment has, in fact, decreased. in our study, we found that roughly one third (around 100 cases) of the 272 screened persons presumably had nihl, taking into account 88 probable cases (column b) and 44 questionable ones (column c + 16 ski slopes). ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21207535